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Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 8, Special Issue 1 (2019)

A walk around A<sup>3</sup> Coupling for the synthesis of Propargylamines

Author(s):

Jasmine Gupta and Rashmi

Abstract:
Propargylamines are a versatile class of compounds which find broad application in many fields of chemistry. This review aims to describe the different strategies developed so far for the synthesis of propargylamines and their derivatives as well as to highlight their reactivity and use as building blocks in the synthesis of chemically relevant organic compounds. In this review, the different synthetic approaches to synthesize propargylamines using different metal and metal ion immobilized ionic liquids and metal catalyst free such as A<sup>3</sup> couplings and C–H functionalization of alkynes, have been described and organized on the basis of the catalysts employed in the syntheses. A metal-free and straightforward greener protocol for the preparation of propargylamine has been reported.

Pages: 676-680  |  1522 Views  545 Downloads

How to cite this article:
Jasmine Gupta and Rashmi. A walk around A<sup>3</sup> Coupling for the synthesis of Propargylamines. J Pharmacogn Phytochem 2019;8(1S):676-680.

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