Journal of Pharmacognosy and Phytochemistry
Vol. 5, Issue 4 (2016)
Cytotoxicity activity of folklore medicinal plants of India
Dora Babu Neerugatti, Mallikarjuna Rao Talluri and Ganga Rao Battu
The present study, cytotoxicity activity of the methanolic extracts of some folklore medicinal (Buchanania axillaris
Desr, Tamilnadia ulignosa
Retz, Phaseolus semierectus
L and Stylosanthes fruticosa
Retz) was evaluated on human cancer cell lines such as colon cancer (HT-29) and breast cancer (MCF-7 and MDA-MB) using MTT assay method. The selected plant extracts showed the dose dependent cytotoxicity activity on the tested cell lines. The cytotoxicity variations on different cell lines were also observed for selected plants extracts. The cytotoxicity of the extracts were increased as the concentration of them was increased. Among all tested plants extracts Phaseolus semierectus
showed the better cytotoxicity activity on tested cell lines. The results support the folkloric usage of the studied plants and confirmed that the studied plant possesses the constituents with cytotoxic properties that can be useful for developing new anticancer agents.
Pages: 220-223 | 1234 Views 43 Downloads
Dora Babu Neerugatti, Mallikarjuna Rao Talluri and Ganga Rao Battu. Cytotoxicity activity of folklore medicinal plants of India. J Pharmacogn Phytochem 2016;5(4):220-223.