Journal of Pharmacognosy and Phytochemistry
Vol. 6, Issue 6 (2017)
Phytochemical and Pharmacological examination of Achyranthes aspera Linn
Author(s):
Dr. Piyush M Maurya
Abstract:
The methanol extract of
achyranthes aspera linn. (family- amaranthaceae) the herb changed into studied for its phytochemical and a few pharmacological activities. The take a look at of the herb extracts indicated the presence of flavonoids, tannins, saponins, and alkaloids. The pharmacological have a look at includes thrombolytic and cytotoxic pastime. They showed substantial cytotoxic impact in brine shrimp lethality bioassay wherein the plant extracts exhibited lc50 =3.80µg/ml and lc90=7.04µg/ml (after 18 hour); lc50 =3.31µg/ml and lc90 =6.36µg/ml (after 21 hour); lc50 =2.18µg/ml and lc90 =5.29µg/ml (after 24 hour). This look at gave a massive indication to using the plant extract as an ability supply for cytotoxic compounds. Inside the thrombolytic hobby of widespread was determined seventy 6.08% and for a. aspera was 36.49%, which shows mild thrombolytic activity. Based at the findings of thrombolytic and toxicological pastime, we can say that
achyranthes aspera may additionally incorporate some novel compounds that own strong anti-mutagenic activity and clot lysis assets.
Pages: 1866-1871 | 1435 Views 438 Downloads
Dr. Piyush M Maurya. Phytochemical and Pharmacological examination of Achyranthes aspera Linn. J Pharmacogn Phytochem 2017;6(6):1866-1871.