Journal of Pharmacognosy and Phytochemistry
Vol. 9, Special Issue 4 (2020)
Microneedle: A useful tool for drug delivery system
Dr. Prateek Mishra, Dr. Vidhi Gautam, Dr. RK Sharma, Dr. Anushri Tiwari and Dr. Alka Sawarkar
Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals. It includes various approaches, formulations, technologies and systems for transporting a pharmaceutical compound in body as needed to safely achieve its desired therapeutic effect Microneedles are three-dimensional (3D) microstructures with micro-scale length (usually <1000 μm) that can pierce the stratum corneum and generate transient micro-channels through which external molecules can passively diffuse into the skin. Microneedles could be designed in a manner that the penetration depth is superficial enough to not touch nerve receptors in the lower reticular dermis, this result in a painless drug administration. It is promising that this microneedle-based transdermal delivery approach will offer a self-management, patient-friendly, and efficient administration route for drug delivery. This system has increased its application to many fields like oligonucleotides delivery, vaccine delivery, insulin delivery, and even in cosmetics.
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Dr. Prateek Mishra, Dr. Vidhi Gautam, Dr. RK Sharma, Dr. Anushri Tiwari and Dr. Alka Sawarkar. Microneedle: A useful tool for drug delivery system. J Pharmacogn Phytochem 2020;9(4S):340-345.